The members of the Field of Focus 1 “Molecular and Cellular Basis of Life “ have committed themselves to the cooperation across institutional boundaries. The joint research projects include initiatives consisting of two up to over a hundred researchers. In the following, we would like to present some of the currently major research activities within the life sciences.
BioQuant, the Center for “Quantitative Analysis of Molecular and Cellular Biosystems” at Heidelberg University was established in 2007 as an interdisciplinary University research center that is solely dedicated to research and training in systems biology. [Homepage]
CellNetworks (founded in 2006), an interdisciplinary cluster aiming at understanding structure, function and evolution of subcellular and supracellular networks, assembles a large number of excellent groups from all Heidelberg molecular life science institutions and specialists from mathematics and computational sciences, chemistry and physics to tackle fundamental questions in network structure and architecture, dynamics and regulation. [Homepage]
Structural biology has revolutionized our understanding of cellular architecture, and the function and mechanism of its components. ConStruct enhances interactions and exchange between Heidelberg groups with strong interests in structural biology. [Homepage]
The DKFZ-ZMBH alliance is a strategic co-operation between research groups of the DKFZ (German Cancer Research Center, Member of the German Helmholtz Association) with focus on cell, and tumor biology and groups of ZMBH (Center for Molecular Biology Heidelberg, part of the University of Heidelberg) with focus on basic research in Molecular and Cellular Life Sciences. [Homepage]
German Centers for Health Research
InnoLife, a consortium of more than 50 core partners (and in addition 90 associate organisations) of leading businesses, research centres and universities from 9 EU countries, has been selected by the European Institute of Innovation and Technology (EIT) as the Knowledge and Innovation Community (KIC) for EIT Health. Central aim of the consortium - in strong collaboration with Heidelberg University and Field of Focus 1 - is to foster innovative products and services for a healthy living and active ageing.
Molecular Medicine Partnership Unit (MMPU)
The MMPU is a successful joint venture between the Medical Faculty of the University of Heidelberg and the European Molecular Biology Laboratory (EMBL) with the mission to strengthen the link between molecular research and medicine.
MMPU Calls! Further information is available at the MMPU webpage [Homepage]
Collaborative Research Centres, funded by the German Research Foundation (DFG) [Homepage]
Maintenance and Differentiation of Stem Cells in Development und Disease (SFB 873, Prof. J. Lohmann)
Environment Specific Control of Immunological Reactivity (SFB 938, Prof. Meuer)
Cellular Quality Control and Damage Response (SFB 1036, Prof. Bukau)
Reactive Metabolites as a Cause of Diabetic Complications (SFB 1118, Prof. Nawroth)
Integrative Analysis of Pathogen Replication and Spread (SFB 1129, Prof. Kräusslich)
Functional ‚Ensembles’: Integration of Cells, Genesis of Activity Patters and Plasticity of Groups of Co-active Neurons in Local Networks (SFB 1134, Prof. Draguhn)
From Nociception to Chronic Pain: Structure-Function Properties of Neural Pathways and Their Reorganisation (SFB 1158, Prof. R. Kuner)
Mechanisms and functions of WnT signaling (SFB 1324, Prof. Holstein)
Vascular Differentiation and Remodeling (SFB/TR 23, Prof. Augustin)
Liver cancer – new mechanistic and therapeutic concepts in a solid tumour model (SFB/TRR 209, Prof. Schirmacher)
Molecular Architecture and Cellular Functions of Lipid/Protein Assemblies (SFB/TR 83, Prof. Söllner)
Cognition-Guided Surgery (SFB/TR 125, Prof. Büchler)
The Skin as Sensor and Effector Organ Orchestrating Local and Systemic Immune Responses (SFB/TRR 156, Prof. Enk)
Determinants and Dynamics of Elimination versus Persistence of Hepatitis Virus Infection (SFB/TRR 179, Prof. Bartenschlager)
Molecular Switches in the Spacio-temporal Control of Cellular Signal Transmission (SFB/TRR 186, Prof. Nickel)
Learning, Memory and Brain Plasticity: Implications for Psychopathology (SFB 636, Prof. Flor, 2004-2015)
Dynamics of Macromolecular Complexes in Biosynthetic Transport (SFB 638, Prof. Wieland, 2004-2015)
Liver Cancer - From Molecular Pathogenesis to Targeted Therapies (SFB/TR 77, Prof. Schirmacher, 2010-2014)
"Unseminar" Bioinformatic (HUB)
Heidelberg Unseminars in Bioinformatics (HUB) take the standard seminar format and turn it inside out, enabling active audience participation, exchange of expertise, open discussion, and fun. Since HUB began in April 2012, several two-hour unseminars have been held, approximately bi-monthly, with a range of topics discussed by thirty to forty participants. [Homepage]
Information about the next HUB is availabe [here].